When you lack sleep, metabolism is greatly altered. For sleep well first thing that happens is a hormonal change, because the alteration that occurs in the brain triggers the stimulation of stress hormone called cortisol. This hormone has enormous power over our metabolism that affects each of our cells. This directly affects the brain and neurotransmitters and the ultimate consequence is neuronal death, passing by anxiety and depression states.
When sleep is altered, produces an increase in blood sugar (without eating anything) because it forces the liver to release glycogen stores in the form of sugar. This can be seen in diabetics, when they have altered their sleep, but do fasting, remain high glucose in their blood, because glucose is released from the liver. On the other hand, cortisol, fat level, has the power to increase its parts: first degrades and on the other hand relocates.
Removes it from the extremities, from the hips and put back on the side of the waist and upper back. In addition, high cortisol impairs protein synthesis and degrades, so begin to weaken hair and his fall occurs. For the same reason, also it decreases the synthesis of muscle, generating muscle atrophy. This is compounded by a sedentary lifestyle that causes chronic fatigue of the insomniac’s people, preventing them from exercising. Muscles are stilling and its structure is replacing adipose tissue. So he is lost muscle mass of arms and legs.
The metabolic changes that generate insomnia occur even without dietary changes. Also they can be produced by anxiety and the need for energy. There are neurotransmitters that are triggered in people who do not sleep, that increase appetite. One is called dimorphic and is a substance that generates increased intake by recording less sleep chronically. Thus begins weight gain. Nobody left untouched cortisol, on his or her way through the metabolism of all our cells. Bone also will decrease in their synthesis and degradation will increase generating eventually osteoporosis.
These reduce the number, quality and lifetime, and so lessen the chances of defenses because cortisol is an suppressant and people sleepless for more than 3 months start to get complicated with bronchial infections or urinary or gastrointestinal infections. The high cortisol promotes increased coagulation and blood viscosity this predisposes to thrombosis events that may be of the retina or ear or small ischemic attacks in the brain.